The application of freeze-drying technology and equipment are inseparable, so far, the form of freeze-dried equipment is divided into intermittent and continuous two categories, the size of the equipment from less than a square meter to dozens of square meters have .
Intermittent lyophilization equipment
Intermittent lyophilization equipment suitable for many varieties of small batch production, especially in the field of food for seasonal food production. Stand-alone operation, if a device fails, it will not affect the normal operation of other devices. Intermittent freeze-drying equipment to facilitate control of the material at different stages of drying temperature and vacuum requirements. Equipment manufacturing and maintenance easy to carry out. However, due to loading, unloading, start-up and other operations take more time, so equipment utilization is low, the production efficiency is not high.
Continuous freeze-drying equipment
At home and abroad began to explore and use continuous vacuum freeze-drying equipment. Continuous equipment is characterized by a single species for a large yield, adequate raw material production, especially for slurry and granular products. Continuous equipment is easy to automate and controls, simplifying manual handling and management, with the main disadvantage of high cost.
With the end of the GMP certification, domestic excellent medical freeze-dried equipment fully entered the modernization stage, full-featured, reliable, stable performance, online cleaning (CIP) or steam sterilization (SIP), the technical indicators Can meet the needs of biological products and pharmaceuticals freeze-dried production. In contrast, foreign varieties of freeze-dried equipment specifications than domestic, complete equipment, energy-efficient structure is more sophisticated, large continuous production of lyophilized equipment. In order to ensure the quality and energy saving of lyophilized products, freeze-drying devices, such as spray freeze-drying devices, are often used in combination with other drying devices.
In the future, how to improve the freeze-drying efficiency, shorten the drying time and save energy will be the goal of the majority of workers in the lyophilization industry under the premise of ensuring product quality.
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