The advantages of freeze-drying:
Drying methods vary widely, such as drying, boiling, drying, spray drying and vacuum drying, etc., but ordinary drying methods are usually above 0 ℃ or higher temperature. Dry products generally have shrinking volume, the problem of hard texture, most of the volatile components will be lost, some of the heat-sensitive material degeneration, inactivation, and even some substances have been oxidized. Therefore, the dried product has a large difference in traits compared to before drying. The lyophilization rule is basically carried out below 0 ° C, ie when the product is frozen and only allowed to rise to a temperature above 0 ° C only if the residual moisture content of the product is reduced later, but generally it does not exceed 40 ° C. Under vacuum conditions, when the water vapor is sublimed directly, the drug remains in the frozen ice shelf, forming a spongy, porous, porous structure that is almost constant in volume after drying. Before use again, just add water for injection and dissolve immediately. Freeze-drying machine relative to conventional methods, lyophilization has the following advantages:
* Many heat-sensitive substances will not be denatured or inactivated.
* When dried at low temperature, some of the volatile components of the material loss is small.
* In the freeze-drying process, the growth of microorganisms and the role of enzymes can not be carried out, so to maintain the original character.
* Since it is dried in a frozen state, the volume is almost the same, the original structure is maintained, and condensation does not occur.
* As the material in the water after pre-freezing in the form of ice crystals, the original inorganic salts dissolved in water dissolved substances are evenly distributed in the material. Sublimation, dissolved in water dissolved matter precipitation, to avoid the general drying method due to internal moisture to the surface of the material carried by the migration of inorganic salts on the surface precipitation caused by the phenomenon of surface hardening.
* After drying the material loose porous, sponge-like, dissolved quickly and completely after adding water, almost immediately restore the original traits.
Due to dry under vacuum, there is very little oxygen, so some easily oxidizable substances are protected.
* Drying can exclude 95% ~ 99% of the water, so that the product can be dried after long-term preservation without deterioration.
* Due to the material in a frozen state, the temperature is very low, so the heat source temperature is not demanding, the use of normal temperature or low temperature heaters to meet the requirements. If the freezer compartment and the drying chamber are separated, the drying chamber need not be adiabatic and will not have much heat loss, so the utilization of thermal energy is economical.
Is the so-called no perfect technology, vacuum freeze-drying technology, the main disadvantage is the high cost. Because it requires vacuum and low temperature conditions, the vacuum freeze-dryer is equipped with a vacuum system and a cryogenic system, resulting in higher capital and operating costs.
Hangzhou Sumer Instrument Co.,Ltd is expert of general laboratory instruments, our main products are incubator, drying oven, autoclave(sterilizer), centrifuge, microscope, spectrophotometer, water distiller, and so on, which are widely use in industry, agriculture, medical application, we offer all kinds of necessities of analytical and measuring instruments for hospital, research institutions, university and government agencies.
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